Humalog Mix50/50 and Breastfeeding

Since no studies have been performed on breastfeeding and Humalog Mix50/50, it is not known if the insulin passes through breast milk. Even if it does, however, it would be destroyed in the digestive tract of the infant (insulin is a protein that is digested and inactivated when taken orally). Before using Humalog Mix50/50, breastfeeding women should consult their healthcare providers.

 

An Overview of Humalog Mix50/50 and Breastfeeding

It is unclear if Humalog® Mix50/50 (insulin lispro protamine/insulin lispro) passes through breast milk. However, this medication is not predicted to cause problems when used while breastfeeding, although breastfeeding can affect insulin requirements. You should talk with your healthcare provider before taking Humalog Mix50/50 if you are breastfeeding or plan to start.
 

Can I Take Humalog Mix50/50 While Breastfeeding?

Most healthcare providers consider insulins (including Humalog Mix50/50) safe for breastfeeding women, much safer than most oral diabetes medications. While no studies have been done to see if Humalog Mix50/50 passes through breast milk in humans, this probably does not matter. Even if it does pass through breast milk, it would be destroyed in the digestive tract of the infant. Insulin is a protein that is digested and inactivated when taken by mouth. This is why insulin cannot be taken by mouth but must be injected.
 
It is important to expect breastfeeding to affect your blood sugar and insulin requirements. Make sure you and your healthcare provider have a plan for safely controlling your blood sugar while nursing.
 

Talking With Your Healthcare Provider About Humalog Mix50/50 and Breastfeeding

Discuss Humalog Mix50/50 and breastfeeding with your healthcare provider.
 Each woman's situation is different, and you and your healthcare provider understand your situation best. After considering what you want and expect, as well as your current health situation, the two of you can make a shared decision about Humalog Mix50/50 and breastfeeding that is right for you.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;