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Drug Interactions

Glynase can potentially interact with a number of medicines (see Glyburide Drug Interactions).

Important Information for Your Healthcare Provider

You should talk with your healthcare provider prior to taking Glynase if you have:
  • Kidney problems, including kidney failure (renal failure)
  • Liver problems, including liver failure or cirrhosis
  • Adrenal insufficiency or adrenal fatigue
  • Pituitary gland problems
  • Any allergies, including to sulfa drugs, foods, dyes, or preservatives.
Also, let your healthcare provider know if you:
  • Are pregnant or thinking of becoming pregnant (see Glyburide and Pregnancy)
  • Are breastfeeding
  • Will be having surgery.
Tell your healthcare provider about all of the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements.
(Click Glyburide Warnings and Precautions to learn more, including information on who should not take this drug.)

Alternatives to Glynase

In general, treatment for type 2 diabetes begins with lifestyle changes (for example, weight loss, exercise, and diet). If lifestyle changes alone are not effective in managing diabetes, medication such as Glynase may be necessary.
The main goal of diabetes medicine is to lower blood sugar levels enough to reduce your risk of developing related problems, such as heart, nerve, eye, or kidney problems. Because Glynase can lower blood sugar levels, people may be able to lower their risk for developing problems related to high blood sugar by taking it.
Glynase is quite effective in controlling blood sugar. It is also generally well tolerated. However, side effects can occur, or the medicine may not work as well as needed. In these cases, Glynase may need to be combined with another diabetes medicine, such as metformin (Glucophage®) or insulin.
You may also wish to consider a substitute for Glynase. These can include other sulfonylureas or diabetes drugs, either by themselves or in combination.
(Click Glyburide Alternatives to learn more about substitutes for Glynase.)
To learn about controlling diabetes through lifestyle choices, click the following eMedTV links:
7 Signs of High Blood Sugar

Glynase Drug Information

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