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Glyburide Problems

Most people are able to take glyburide (DiaBeta®, Glynase®, Micronase®) without any problems. However, some people do experience side effects, such as:
  • Stomach problems (nausea, heartburn, and a feeling of fullness in the throat or upper chest)
  • Allergic skin reactions (rashes, itching, hives, or sensitivity to the sun).
In most cases, side effects of the drug are mild, but potentially serious problems are also possible with glyburide. For example, some people develop symptoms of liver problems, such as:
  • Yellow skin or whites of the eyes (jaundice)
  • Dark urine
  • Stomach pain in the upper-right area.
Fever, infections, injury, or surgery can temporarily increase your blood sugar, even in people with well-controlled diabetes -- glyburide may not be enough to treat your diabetes at these times, and the use of insulin may be required. Contact your healthcare provider if you have a fever, infection, injury, or will be having surgery.
(To learn more about the problems that can occur with glyburide, click Glyburide Side Effects or Glyburide Warnings and Precautions.)
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