Glyburide (
DiaBeta®,
Glynase®,
Micronase®) is a
type 2 diabetes medicine that may be used in people who cannot lower blood sugar levels effectively through lifestyle changes such as weight loss, diet, and exercise.
Glyburide affects the body in a couple of ways. The medication belongs to a class of drugs known as sulfonylureas, which means that it works by helping the
pancreas produce more
insulin. It may also help to lower blood sugar by improving insulin resistance, thereby helping the cells remove more sugar from the blood.
In some cases, however, this drug is not effective enough on its own, and glyburide may need to be combined with other
diabetes medicines. For example, if type 2 diabetes is left untreated for a long time, the pancreas may not be able to make enough insulin anymore. Thus, using glyburide alone will not be effective. A person would need to take another
diabetes medication or take insulin along with glyburide.
(To learn more about the drug's effectiveness, click Glyburide. This overview article offers an in-depth description of how this medicine works, possible side effects, and more.)