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Glyburide Drug Interactions

Estrogens
If glyburide and estrogens are combined, this can make glyburide less effective, possibly increasing your chance of high blood sugar (hyperglycemia). To prevent this, you may need to be monitored more closely, and your healthcare provider may need to adjust your glyburide dose, especially when starting or stopping an estrogen.
 
Fluoroquinolone Antibiotics
Taking glyburide with fluoroquinolones can increase your risk of low blood sugar (hypoglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your glyburide dose, especially when starting or stopping a fluoroquinolone, depending on your particular situation.
 
Fluoxetine
Taking glyburide with fluoxetine can increase your risk of low blood sugar (hypoglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your glyburide dosage, especially when starting or stopping fluoxetine.
 
Isoniazid
If glyburide and isoniazid are taken together, this can make glyburide less effective, which may increase your chance of high blood sugar (hyperglycemia). To prevent this, you may need to be monitored more closely, and your healthcare provider may need to adjust your glyburide dose, especially when starting or stopping isoniazid.
 
Monoamine Oxidase Inhibitors
Taking glyburide with MAOIs can increase your risk of low blood sugar (hypoglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your glyburide dose, especially when starting or stopping an MAOI.
 
Niacin
If glyburide is taken with niacin, this can make glyburide less effective, potentially increasing your chance of high blood sugar (hyperglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your glyburide dose, especially when starting or stopping niacin.
7 Signs of High Blood Sugar

Glyburide Medication Information

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