Diabetes Channel
Topics
Medications
Quicklinks
Related Channels

Glyburide Drug Interactions

Glyburide Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when glyburide is combined with any of the medications listed above.
 
ACE Inhibitors
ACE inhibitors may increase the risk of low blood sugar (hypoglycemia) with glyburide. Check with your healthcare provider before taking glyburide with an ACE inhibitor. You may need to monitor your blood sugar more closely, especially when starting or stopping the ACE inhibitor.
 
Beta Blockers
Taking glyburide with beta blockers can increase your risk of low blood sugar (hypoglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your glyburide dose, especially when starting or stopping a beta blocker.
 
Bosentan
Combining bosentan with glyburide may increase the risk of liver problems. In general, these medications should not be taken together.
  
Certain Decongestants
If glyburide is taken with certain decongestants, this can make glyburide less effective, possibly increasing your chance of high blood sugar (hyperglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your glyburide dose, especially when starting or stopping decongestants, to prevent this interaction from occurring.
 
Clarithromycin
Taking glyburide with clarithromycin can increase your risk of low blood sugar (hypoglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your glyburide dose, especially when starting or stopping clarithromycin.
  
Corticosteroids
If glyburide and corticosteroids are taken together, this can make glyburide less effective, which may increase your chance of high blood sugar (hyperglycemia). To prevent this, you may need to be monitored more closely, and your healthcare provider may need to adjust your glyburide dose, especially when starting or stopping a corticosteroid.
 
Cyclosporine
Glyburide may increase the level of cyclosporine in the blood. If you take these medications together, your healthcare provider may decide to monitor the level of cyclosporine in your blood and adjust your cyclosporine dosage as necessary. This is especially important when you start or stop taking glyburide (or even when you change your dosage).
 
Disopyramide
Taking glyburide with disopyramide can increase your risk of low blood sugar (hypoglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your dosage of glyburide, especially when starting or stopping disopyramide.
 
Diuretics
Combining glyburide with diuretics can make glyburide less effective, potentially increasing your chance of high blood sugar (hyperglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your glyburide dose, especially when starting or stopping a diuretic.
Type 2 Diabetes: Fact or Fiction

Glyburide Medication Information

Terms of Use
Advertise with Us
Contact Us
About eMedTV
Privacy Policy
Copyright © 2006-2017 Clinaero, Inc.
eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.