Although most people have no problems with glyburide (DiaBeta®, Glynase®, Micronase®), it is not free of dangerous risks. Before starting treatment, make sure your healthcare provider is aware of any other medical conditions you have and any other medications you are taking, including nonprescription medications, vitamins, and herbal supplements.
In clinical trials, glyburide was reported to cause side effects such as:
- Stomach problems (nausea, heartburn, and a feeling of fullness in the throat or upper chest) -- occurring in up to 1.8 percent of people
- Allergic skin reactions (rashes, itching, hives, or sensitivity to the sun) -- in up to 1.5 percent.
In rare cases, some side effects can occur when taking glyburide with alcohol, including:
- Stomach cramps
Other safety concerns with glyburide apply to women who are pregnant or breastfeeding, as well as people who have certain allergies. Also, it could be dangerous for certain people to take glyburide, such as those with liver problems, adrenal fatigue, or other medical conditions.
(Click Glyburide Side Effects or Glyburide Warnings and Precautions to learn more about the dangers of glyburide, including details on who should avoid the drug altogether.)