DiaBeta and Micronase are similar, and both contain glyburide; however, Glynase is formulated differently. Glynase contains
micronized glyburide, which is made into small particles that are better absorbed into the body. These two forms are not interchangeable.
An easy way to tell if you are taking unmicronized or micronized glyburide is by looking at the strength: unmicronized glyburide comes in 1.25-mg, 2.5-mg, and 5-mg tablets. Micronized glyburide comes in 1.5-mg, 3-mg, 4.5-mg, and 6-mg tablets.
When a healthcare provider starts someone on this drug, the usual dosage is glyburide 2.5 mg to 5 mg daily (1.5 mg to 3 mg daily if using micronized glyburide), taken with breakfast or the first main meal. In certain situations, a smaller dosage may be necessary.
(To learn how your healthcare provider will determine the right strength of glyburide for your situation, click Glyburide Dosing. This article also features helpful tips on how to take this medication.)
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