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Glucovance Warnings and Precautions

Some Glucovance warnings and precautions to be aware of include potential drug interactions, the safety of taking Glucovance while pregnant, and a possible increased risk of death due to heart or blood vessel problems in some people taking this drug. A few of the conditions that you should let your healthcare provider know about before taking Glucovance include kidney or liver problems, congestive heart failure, and adrenal insufficiency.

Glucovance: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking Glucovance® (glyburide and metformin) if you have:
  • Congestive heart failure (CHF)
  • Adrenal insufficiency or pituitary insufficiency
  • Kidney problems, including kidney failure (renal failure)
  • Liver problems, including liver failure or cirrhosis
  • Low vitamin B12 levels (pernicious anemia)
  • A history of a heart attack or stroke
  • Adrenal insufficiency or adrenal fatigue
  • Pituitary gland problems
  • An upcoming surgery or procedure (including x-rays and other radiology procedures)
  • Glucose-6-phosphate dehydrogenase deficiency (G6PD deficiency) 
  • Any allergies, including allergies to sulfa drugs, food, dyes, or preservatives.
Also let your healthcare provider know if you:
  • Are pregnant or thinking of becoming pregnant
  • Are breastfeeding
  • Drink alcohol.
Tell your healthcare provider about all of the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.
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