Glucovance (Cont.)

Glucovance Effects

There have been several studies looking at the effects of Glucovance for type 2 diabetes.
 
Glucovance and Hemoglobin A1c
Hemoglobin A1c (HbA1c) is a test used to measure long-term blood sugar control. For people without diabetes, HbA1c results are usually less than 6 percent. People with diabetes usually have higher results. In one study, people taking Glucovance lowered their HbA1c by up to 1.53 percent on average. In the same study, people taking glyburide or metformin alone did not decrease their HbA1c levels as much as people taking Glucovance.
 
Studies have shown that the higher the HbA1c, the greater the chance of developing long-term problems related to diabetes. Some of these problems include heart disease, diabetic retinopathy, diabetic neuropathy, and diabetic nephropathy. By getting blood sugar levels under control with Glucovance, it may be possible to decrease the chances of developing these diabetes complications.
 
Glucovance and Fasting Blood Sugar
Fasting blood sugar is another way to study the effects of diabetes drugs. In studies, people taking Glucovance decreased their fasting blood sugar levels by 41.5 mg/dL on average. People taking glyburide or metformin alone did not decrease their fasting blood sugar levels as much as people taking Glucovance.
 

When and How to Take Glucovance

Some general considerations for when and how to take Glucovance include:
 
  • Glucovance comes in tablet form. It should be taken by mouth once or twice daily with meals.
     
  • In order to prevent an upset stomach, it is best to take Glucovance with food.
     
  • Glucovance should be taken at the same time(s) each day to maintain an even level of the drug in your blood.
     
  • For Glucovance to work properly, it must be taken as prescribed. Glucovance will not work if you stop taking it.
     
(Glucovance Continued: Page 3)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;