Glucovance Drug Interactions

Phenytoin (Dilantin)
Taking Glucovance with phenytoin can make Glucovance less effective, increasing your chance of high blood sugar (hyperglycemia). If you are taking Glucovance along with phenytoin, you may need to be monitored more closely, and your healthcare provider may need to adjust your Glucovance dose -- especially when you are starting or stopping phenytoin.
 
Probenecid (Benuryl, ColBenemid)
Taking Glucovance with probenecid can increase your risk of low blood sugar (hypoglycemia). If you are taking Glucovance along with probenecid, you may need to be monitored more closely, and your healthcare provider may need to adjust your Glucovance dose -- especially when you are starting or stopping probenecid.
 
Salicylates
Taking Glucovance with salicylates can increase your risk of low blood sugar (hypoglycemia). If you are taking Glucovance with a salicylate, you may need to be monitored more closely, and your healthcare provider may need to adjust your Glucovance dose -- especially when you are starting or stopping a salicylate.
 
Sulfonamides
Taking Glucovance with sulfonamides can increase your risk of low blood sugar (hypoglycemia). If you are taking Glucovance along with a sulfonamide, you may need to be monitored more closely, and your healthcare provider may need to adjust your Glucovance dose -- especially when you are starting or stopping a sulfonamide.
 
Thyroid Medications
Taking Glucovance with thyroid medications can make Glucovance less effective, increasing your chance of high blood sugar (hyperglycemia). If you are taking Glucovance along with a thyroid medication, you may need to be monitored more closely, and your healthcare provider may need to adjust your Glucovance dose -- especially when you are starting or stopping a thyroid medication.
(Glucovance Drug Interactions Continued: Page 6)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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