Glucovance Drug Interactions

Monoamine Oxidase Inhibitors (MAOIs)
Taking Glucovance with monoamine oxidase inhibitors can increase your risk of low blood sugar (hypoglycemia). If you are taking Glucovance along with an MAOI, you may need to be monitored more closely, and your healthcare provider may need to adjust your Glucovance dose -- especially when you are starting or stopping an MAOI.
 
Niacin (Nicotinic Acid, Niaspan, Niacor, Nicolar)
Taking Glucovance with niacin can make Glucovance less effective, increasing your chance of high blood sugar (hyperglycemia). If you are taking Glucovance along with niacin, you may need to be monitored more closely, and your healthcare provider may need to adjust your Glucovance dose -- especially when you are starting or stopping niacin.
 
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
Taking Glucovance with an NSAID can increase your risk of low blood sugar (hypoglycemia). If you are taking Glucovance along with an NSAID, you may need to be monitored more closely, and your healthcare provider may need to adjust your Glucovance dose -- especially when you are stopping or starting an NSAID.
 
Oral Contraceptives
Taking Glucovance with oral contraceptives (birth control pills) can make Glucovance less effective, increasing your chance of high blood sugar (hyperglycemia). If you are taking Glucovance along with an oral contraceptive, you may need to be monitored more closely, and your healthcare provider may need to adjust your Glucovance dose -- especially when you are starting or stopping an oral contraceptive.
 
Phenothiazines
Taking Glucovance with phenothiazines can make Glucovance less effective, increasing your chance of high blood sugar (hyperglycemia). If you are taking Glucovance along with a phenothiazine, you may need to be monitored more closely, and your healthcare provider may need to adjust your Glucovance dose -- especially when you are starting or stopping a phenothiazine.
(Glucovance Drug Interactions Continued: Page 5)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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