Glucovance Drug Interactions

Diuretics
Taking Glucovance with diuretics can make Glucovance less effective, increasing your chance of high blood sugar (hyperglycemia). If you are taking Glucovance along with a diuretic, you may need to be monitored more closely, and your healthcare provider may need to adjust your Glucovance dose -- especially when you are starting or stopping a diuretic.
 
Taking Glucovance with furosemide (a diuretic) can affect the levels of both furosemide and Glucovance in your blood. This may increase your risk of Glucovance side effects and may make furosemide less effective. If you are taking Glucovance along with furosemide, your healthcare provider may need to adjust your doses of these medications.
 
Estrogens
Taking Glucovance with estrogens can make Glucovance less effective, increasing your chance of high blood sugar (hyperglycemia). If you are taking Glucovance along with estrogens, you may need to be monitored more closely, and your healthcare provider may need to adjust your Glucovance dose -- especially when you are starting or stopping an estrogen.
 
Fluoroquinolone Antibiotics
Taking Glucovance with fluoroquinolones can increase your risk of low blood sugar (hypoglycemia). If you are taking these drugs together, you may need to be monitored more closely, and your healthcare provider may need to adjust your Glucovance dose -- especially when you are starting or stopping a fluoroquinolone.
 
Isoniazid
Taking Glucovance with isoniazid can make Glucovance less effective, increasing your chance of high blood sugar (hyperglycemia). If you are taking these medicines together, you may need to be monitored more closely, and your healthcare provider may need to adjust your Glucovance dose -- especially when you are starting or stopping isoniazid.
(Glucovance Drug Interactions Continued: Page 4)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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