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Glucovance Drug Interactions

Glucovance Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Glucovance is combined with any of the drugs listed above.
 
Beta Blockers
Taking Glucovance with beta blockers can increase your risk of low blood sugar (hypoglycemia). If you are taking Glucovance along with a beta blocker, you may need to be monitored more closely, and your healthcare provider may need to adjust your Glucovance dose -- especially when you are starting or stopping a beta blocker.
 
Bosentan
Combining Glucovance with bosentan may cause increased liver enzymes. These medications should not be combined. 
 
Calcium Channel Blockers
Taking Glucovance with calcium channel blockers can make Glucovance less effective, increasing your chance of high blood sugar (hyperglycemia). If you are taking these medicines together, you may need to be monitored more closely, and your healthcare provider may need to adjust your Glucovance dose -- especially when you are starting or stopping a calcium channel blocker.
 
Certain Decongestants
Taking Glucovance with certain decongestants can make Glucovance less effective, increasing your chance of high blood sugar (hyperglycemia). Decongestants are in many cough and cold products, so be sure to talk with your healthcare provider before taking any of these products.
 
Cimetidine (Tagamet)
Taking Glucovance with cimetidine can increase the level of Glucovance in your blood, increasing your risk of side effects. Your healthcare provider may need to adjust your dose of these medications or may suggest an alternative to cimetidine.
 
Corticosteroids
Taking Glucovance with corticosteroids can make Glucovance less effective, increasing your chance of high blood sugar (hyperglycemia). If you are taking these drugs together, you may need to be monitored more closely, and your healthcare provider may need to adjust your Glucovance dose -- especially when you are starting or stopping a corticosteroid.
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