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Glucovance Dosage

The recommended starting Glucovance dose for those who are not taking metformin or glyburide is 1.25 mg/250 mg once daily with meals. If necessary, your healthcare provider may slowly increase your Glucovance dosage up to a maximum dose of 20 mg/2000 mg per day. Glucovance dosing will vary depending on several factors, such as how well your diabetes is controlled, other medical conditions you may have, and other medications you may be taking.

Glucovance Dosing: An Introduction

Glucovance® (glyburide and metformin) is a combination of two different diabetes drugs: glyburide (DiaBeta®, Glynase®, or Micronase®) and metformin hydrochloride (Fortamet®, Glucophage®, Glucophage XR®, Glumetza®, or Riomet®). The dose of Glucovance your healthcare provider prescribes will vary depending on a number of factors, including:
  • How well your diabetes is controlled
  • Other medical conditions you may have
  • Other medications you may be currently taking.
As always, do not adjust your dose unless your healthcare provider specifically instructs you to do so.

Glucovance Dosage for People New to Metformin and Glyburide

If you are not taking either metformin or glyburide, the recommended starting dose is Glucovance 1.25 mg/250 mg once daily with meals. If your diabetes is poorly controlled (if you have an HbA1c level greater than 9 percent or a fasting blood sugar level greater than 200 mg/dL), the recommended starting dose is Glucovance 1.25 mg/250 mg twice daily with meals. Your healthcare provider can slowly increase your dose if necessary, up to a total of Glucovance 20 mg/2000 mg per day.
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