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Glucovance and Pregnancy

The FDA has classified Glucovance as a pregnancy Category B medication, meaning that it does not appear to cause harm to the fetus in animal studies. It is important to note, however, that Glucovance and pregnancy have not been studied together in humans, so the possible risks of taking Glucovance during pregnancy are not known. A pregnant woman may take Glucovance if her healthcare provider decides that its benefits outweigh the possible risks to her unborn child.

Is Glucovance Safe During Pregnancy? -- An Overview

For people who are pregnant, Glucovance® (glyburide and metformin) is generally considered safe. This is based on animal studies that looked at the effects of Glucovance during pregnancy.

Glucovance and Pregnancy Category B

The U.S. Food and Drug Administration (FDA) uses a pregnancy category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category B is given to medicines that have not been studied in pregnant humans, but do not appear to cause harm to the fetus in animal studies.
It is important to note that animals do not always respond to medicines in the same way that humans do, and the full risks of using Glucovance in pregnant women are not known. A pregnancy Category B medicine may be given to a pregnant woman if her healthcare provider believes that its benefits to the pregnant woman outweigh any possible risks to her unborn child.
Prior to taking Glucovance, let your healthcare provider know if you are pregnant or thinking about becoming pregnant. Your healthcare provider will consider both the benefits and the risks of taking Glucovance during pregnancy before making a recommendation for your particular situation.
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