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Glucovance and Hypoglycemia

Several side effects are possible with Glucovance, and hypoglycemia is common. During clinical studies, hypoglycemia occurred in up to 37.7 percent of people taking the drug. Symptoms can include sweating, shakiness, and blurry vision. Because low blood sugar levels can cause serious or even life-threatening complications, it is important to be aware of the possible signs and know what to do if they occur.

The Link Between Glucovance and Hypoglycemia

Glucovance® (glyburide and metformin) does have an effect on blood sugar levels. For some people, the medication can cause blood sugar levels to drop too low (a condition called hypoglycemia).
 

How Commonly Does Hypoglycemia Occur With Glucovance?

During clinical studies, hypoglycemia occurred in up to 37.7 percent of people taking Glucovance. This is most likely due to the glyburide component. Glyburide causes the pancreas to make more insulin, and too much insulin can cause hypoglycemia. Metformin, the other component, does not usually cause hypoglycemia by itself.
 
It is important to note that in these trials, no one required medical attention or medication to treat their hypoglycemia. They were able to manage the condition on their own.
 
Hypoglycemia symptoms can vary, depending on a number of factors, including how low the blood sugar levels are. Some examples of early symptoms of low blood sugar include:
 
  • Sweating
  • Shakiness
  • Extreme hunger
  • Dizziness
  • Cold sweats
  • Blurry vision.
     
More severe symptoms include:
 
  • Changes in behavior, such as irritability
  • Loss of coordination
  • Difficulty speaking
  • Confusion
  • Seizures
  • Loss of consciousness
  • Coma
  • Loss of life.
     
If you are taking Glucovance and hypoglycemia symptoms occur, contact your healthcare provider immediately or seek emergency medical care and stop taking the medicine. If your healthcare provider believes that hypoglycemia is causing your symptoms, he or she may recommend that you treat the problem immediately by eating or drinking something with sugar in it, such as:
 
  • Orange juice
  • Hard candy
  • A tablespoon of honey
  • A tablespoon of granulated sugar.
 
Healthy Eating for People With Diabetes

Glucovance Drug Info

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