Side Effects of Glipizide

Although most people tolerate the drug without problems, side effects of glipizide are possible, such as dizziness, diarrhea, and nervousness. In many cases, these side effects are minor and easily treated by you or your healthcare provider. However, some glipizide side effects should be reported to your doctor, including chest pain, shortness of breath, or signs of an allergic reaction.

 

Side Effects of Glipizide: An Introduction

As with any medicine, side effects are possible with glipizide (Glucotrol®) or glipizide extended release (Glucotrol XL®). However, not everyone who takes the drug will experience side effects. In fact, most people tolerate glipizide quite well. If side effects do occur, in most cases, they are minor and either require no treatment or can easily be treated by you or your healthcare provider.
 
(The side effects of glipizide discussed below are not a complete list of reported side effects. Your healthcare provider can discuss a more complete list with you.)
 

Common Side Effects of Glipizide

Glipizide has been studied thoroughly in clinical trials in which the side effects reported by a group of people taking the drug are documented and compared to another group not taking the medicine.
 Based on the studies of extended release glipizide, the most common side effects include:
 
  • Dizziness -- occurring in up to 6.8 percent of people
  • Diarrhea -- in up to 5.4 percent
  • Nervousness -- in up to 3.6 percent
  • Tremor or shakiness -- in up to 3.6 percent
  • Gas -- in up to 3.2 percent.
     
Other common side effects of glipizide (occurring in 1 to 3 percent of people) include:
 
(Side Effects of Glipizide Continued: Page 2)
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;