Side Effects of Glipizide
Common Side Effects of Glipizide
Glipizide has been studied thoroughly in clinical trials in which the side effects reported by a group of people taking the drug are documented and compared to another group not taking the medicine. This way, it is possible to see what side effects occur, how often they appear, and how they compare to the group not taking the medicine.
Based on the studies of extended-release glipizide, the most common side effects include:
- Dizziness -- occurring in up to 6.8 percent of people
- Diarrhea -- in up to 5.4 percent
- Nervousness -- in up to 3.6 percent
- Tremor or shakiness -- in up to 3.6 percent
- Gas -- in up to 3.2 percent.
Other common side effects of glipizide (occurring in 1 to 3 percent of people) include:
- General pain
- Depression (see Glipizide and Depression)
- Low blood sugar (see Glipizide and Blood Sugar)
- Blurred vision.
Rare Side Effects of GlipizideRare glipizide side effects have happened in only a few people taking the drug. Because these side effects are so uncommon, it is difficult to tell whether they are caused by glipizide or something else.
Based on the studies of extended-release glipizide, some of these rare side effects include but are not limited to:
- Vertigo (a spinning sensation)
- Decreased libido or sex drive (see Glipizide Sexual Side Effects)
- Migraine headaches
- Low sodium in the blood (hyponatremia)
- Reactions with alcohol, causing:
- Stomach upset
- Stomach cramps.
Oral diabetes medications, including glipizide, may increase the risk of death due to heart or blood vessel problems, compared to diabetes treatment with diet or insulin. This warning is based on one research study that looked at a medication similar to glipizide. However, it is unclear at this time how important this risk may be in people taking glipizide.