Glipizide Uses: An Overview
Glipizide (
Glucotrol®) is a prescription medication licensed to treat
type 2 diabetes. A long-acting form, extended release glipizide (Glucotrol XL
®), is also available. Extended release glipizide tablets slowly release the medication, providing a more even level of glipizide in the blood.
Glipizide is often used when blood sugar cannot be controlled by diet and exercise alone. It can be used alone or in combination with other
diabetes medications.
Glipizide Uses for Type 2 Diabetes
Type 2 diabetes is the most common type of diabetes
(see
Diabetes Types). It is also sometimes called adult-onset diabetes or non-
insulin-dependent diabetes. Type 2 diabetes is a condition involving insulin resistance. With insulin resistance, the cells of the body do not respond to insulin as well as they normally should. As a result, the cells do not take sugar out of the blood very well. This is why people with the condition have high blood sugar.
Glipizide is used to treat type 2 diabetes in people who cannot lower blood sugar sufficiently through lifestyle changes (such as weight loss, diet, and exercise). It works by increasing the production of insulin in the
pancreas. It may also help to lower blood sugar by improving insulin resistance. This means that glipizide may help the cells take more sugar from the blood.
In some people, glipizide may need to be combined with other diabetes medicines. For example, if type 2 diabetes is untreated for a very long time, the pancreas may not be able to make enough insulin anymore. In these cases, using glipizide alone will not be effective. These people will need to take insulin along with glipizide.