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Glipizide ER (Extended-Release)

The diabetes drug Glipizide (Glucotrol®) is available in two forms: regular tablets and extended-release (ER) tablets.
The regular tablets come in two strengths:
  • Glipizide 5 mg
  • Glipizide 10 mg.
The extended-release tablets are available in three strengths:
  • Glipizide extended-release 2.5 mg
  • Glipizide extended-release 5 mg
  • Glipizide extended-release 10 mg.
The dosage your healthcare provider recommends will vary, based on your current health situation, including factors such as how well your diabetes is controlled and whether you are taking other medications. If you have been prescribed the extended-release tablets, keep in mind that you must swallow them whole -- do not crush, chew, or break them.
Extended-release glipizide needs time to be released into your digestive tract. Therefore, if you have problems that cause medications to move too quickly through the digestive tract (such as diarrhea), you may not absorb the full amount of the medicine. In this case, another product may be recommended.
(Click Glipizide to learn more about both the regular and extended-release versions of this drug. This article also outlines potential side effects and explains what to do if you miss a dose.)
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