Glipizide Drug Interactions

When certain medications are taken with glipizide, drug interactions may occur, such as an increased risk of high or low blood sugar. The medications may also lose their effectiveness. Drugs that can interact with glipizide include beta blockers, calcium channel blockers, and oral contraceptives. If glipizide drug interactions are a concern, your healthcare provider may adjust your dosages or monitor you more closely.

An Overview of Glipizide Drug Interactions

 Glipizide (Glucotrol®) or glipizide extented release (Glucotrol XL®) can potentially interact with many drugs. Some of the drugs that may lead to glipizide interactions include:
 
 
 
 
 
 
    • Betamethasone (Celestone®)
    • Cortisone
    • Dexamethasone (Decadron®)
    • Fludrocortisone (Florinef®)
    • Hydrocortisone (Cortef®)
    • Methylprednisolone (Depo-Medrol®, Medrol®)
    • Prednisolone (Ovapred®, Pediapred®)
    • Prednisone
    • Triamcinolone (Kenalog®, Aristospan®). 
 
  • Diuretics, such as:
 
 
  • Estrogens
     
  • Isoniazid
     
  • Monoamine oxidase inhibitors (MAOIs), including:
 
 
  • Niacin (nicotinic acid, Niaspan®, Niacor®, Nicolar®)
     
  • Nonsteroidal anti-inflammatory drugs (NSAIDs), such as:
 
 
 
 
  • Phenytoin (Dilantin®)
     
  • Probenecid (Benuryl®, ColBenemid®)
     
  • Salicylates, such as:
 
    • Aspirin
    • Choline magnesium trisalicylate (Trilisate®)
    • Diflunisal (Dolobid®)
    • Salsalate (Salflex®, Disalcid®, Amigesic®).
 
  • Sulfonamides ("sulfa drugs"), including:
 
    • Sulfadiazine
    • Sulfadoxine (Fansidar®)
    • Sulfamethoxazole (Bactrim®, Septra®)
    • Sulfisoxazole (Gantrisin®).
 
  • Thyroid medications, such as:
 
 

Add
Email
Print
(Glipizide Drug Interactions Continued: Page 2)
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
Other Articles in This eMedTV Presentation
Referring Pages Articles