Glipizide Dosing

The glipizide dosing guidelines your healthcare provider will follow depend on several factors, such as how well your diabetes is controlled, other medical conditions you may have, and other medications you may be taking. The recommended dosage when starting the drug is 5 mg, taken once daily before breakfast. Your healthcare provider may gradually increase your glipizide dosing, if necessary, to a maximum of 40 mg per day.

 

An Introduction to Glipizide Dosing

The dosage of glipizide (Glucotrol®) or glipizide extended release (Glucotrol XL®) your healthcare provider prescribes will vary, depending on a number of factors, including:
 
  • How well your diabetes is controlled
  • Other medical conditions you may have
  • Other medications you are currently taking.
     
As is always the case, do not adjust your glipizide dose unless your healthcare provider specifically instructs you to do so.
 

Glipizide Dosing for Type 2 Diabetes

For regular glipizide (not extended release), the recommended starting dose is glipizide 5 mg, taken once daily before breakfast. For elderly people or people with liver problems, the recommended starting dose is lower (glipizide 2.5 mg, taken once daily before breakfast).
 
Your healthcare provider may increase your dose slowly if necessary, up to a maximum of 40 mg total per day. For people taking more than 15 mg of glipizide per day, the dose should be split up into at least two doses and taken before meals.
 

Extended Release Glipizide Dosing for Type 2 Diabetes

For extended release glipizide, the recommended starting dose is glipizide extended release 5 mg, taken once daily with breakfast.
 The dose may be increased if necessary to control blood sugar, up to 20 mg, taken once daily.
 
(Glipizide Dosing Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;