Fenugreek Drug Interactions

A number of medications could potentially interact negatively with fenugreek. Drug interactions may occur if the herbal supplement is taken with diabetes medicines and medications that "thin" the blood, such as aspirin, warfarin, or NSAIDs. Fenugreek drug interactions can increase the risk of low blood sugar and the risk of bleeding, including dangerous internal bleeding.

 

An Introduction to Fenugreek Drug Interactions

Even though it is a "natural" product,
 fenugreek (Trigonella foenum-graecum) can potentially interact with several medicines. Some of the medicines that may lead to fenugreek drug interactions include:
 
  • Diabetes medications
  • Medications that "thin" the blood (they have anticoagulant or antiplatelet activity), such as:
 
    • Aspirin (Bayer® and others)
    • Clopidogrel (Plavix®)
    • Heparin or heparin-like products, including dalteparin (Fragmin®), enoxaparin (Lovenox®), or tinzaparin (Innohep®)
    • Nonsteroidal anti-inflammatory drugs (NSAIDs), such as:
 
o Warfarin (Coumadin®, Jantoven®).
(Fenugreek Drug Interactions Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;