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Exubera Warnings and Precautions

Specific Exubera Warnings and Precautions

Warnings and precautions to be aware of before taking Exubera include the following:
  • In studies, people who took Exubera had an increased risk of lung cancer. However, it is not entirely clear if Exubera was to blame. All of the people in Exubera studies who developed lung cancer had a previous history of cigarette smoking.


  • Exubera works faster than regular insulin. Therefore, make sure to begin eating within 10 minutes after taking your dose. 


  • The medication can cause low blood sugar (hypoglycemia) in some people. This is more common in elderly people and in people with adrenal, pituitary, liver, or kidney problems, as well as during fasting before surgery and after prolonged exercise. Symptoms of low blood sugar include irritability, trembling, cold sweats, or blurry vision, among other things.
  • Fever, infections, injury, or surgery can temporarily increase your blood sugar, even in people with well-controlled diabetes. Contact your healthcare provider if you have a fever, infection, injury, or will be having surgery. Also, make sure you know the symptoms of high blood sugar and how to check your blood sugar levels.
  • Careful monitoring of blood sugar is necessary any time diabetes drugs are changed. This is also recommended for all people taking Exubera.
  • The medication is not recommended for people with lung problems, such as asthma and chronic obstructive pulmonary disease (COPD). Your lung function should be checked before starting Exubera, since it can have a negative effect on lung function. Your healthcare provider should also monitor your lungs during treatment to make sure the drug is not causing lung problems.
  • Exubera does not need to be stopped in people with respiratory infections (such as the common cold). However, close monitoring is recommended in these situations.
  • The medication has not been studied in people with liver or kidney problems. Your dose may need to be adjusted in these situations.
  • As with all insulins, Exubera can cause allergic reactions, including wheezing or difficulty breathing. Be sure to tell your healthcare provider if you are having an allergic reaction.
  • Exubera is considered a pregnancy Category C medication. This means that the full risks of using it during pregnancy are not known. Therefore, talk to your healthcare provider if you are pregnant or thinking of becoming pregnant while taking the drug (see Exubera and Pregnancy).
  • Exubera passes through breast milk. Therefore, if you are breastfeeding or plan to start, talk to your healthcare provider about using the drug while breastfeeding.
  • Exubera can interact with certain medications (see Exubera Drug Interactions).
Diabetes Tips for Seniors

Exubera Drug Information

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