Duetact Warnings and Precautions

People who are allergic to any components of Duetact or have diabetic ketoacidosis should not take Duetact. Warnings and precautions also include side effects that may occur, such as fluid retention and increased liver enzymes, and existing medical conditions that should be discussed with your healthcare provider, including liver problems, and heart problems. Duetact warnings and precautions also extend to women who are pregnant or breastfeeding.

Duetact: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking
 Duetact® (pioglitazone and glimepiride) if you have:
 
  • Kidney problems, including kidney failure
  • Liver problems, including liver failure or cirrhosis
  • Heart problems of any kind, especially congestive heart failure (CHF)
  • Adrenal insufficiency or adrenal fatigue
  • Pituitary gland problems
  • An upcoming surgery
  • Glucose-6-phosphate dehydrogenase deficiency (G6PD deficiency) 
  • Any allergies, including allergies to sulfa drugs, foods, dyes, or preservatives.
     
Also let your healthcare provider know if you are:
 
  • Pregnant or thinking of becoming pregnant
  • Having problems getting pregnant
  • Breastfeeding
  • Premenopausal without regular menstrual periods.
     
In addition, tell your healthcare provider about all other medicines you may be taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 
Duetact Warnings and Precautions Article Continues on Next Page >
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD
 
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