Causes of Diabetes

With type 1 diabetes, the causes of diabetes involve the destruction of the pancreas' ability to produce insulin. Scientists have identified risk factors that increase the chances of developing type 2 diabetes; however, the specific causes of diabetes of this type are unknown. Causes of diabetes in pregnant women are linked to hormonal changes and weight gain associated with pregnancy.

 

Causes of Diabetes: An Overview

Diabetes is a group of diseases marked by high levels of blood glucose resulting from defects in insulin production, insulin action, or both. Diabetes can lead to serious complications and premature death, but people with diabetes can take steps to control the disease and lower the risk of complications.
 
The three types of diabetes are:
 

Causes of Diabetes: Type 1

The cause of type 1 diabetes is the destruction of the insulin-producing beta cells of the
 pancreas by a person's own immune system. These beta cells of the pancreas are the only cells in the body that make the hormone insulin that regulates blood glucose.
 
A combination of genetic and environmental factors put people at increased risk for type 1 diabetes. Researchers are working to identify these factors and to stop the autoimmune process that destroys the pancreas. Currently, there is no known way to prevent type 1 diabetes.
 
Type 1 diabetes can occur at any age, but it most often occurs in children and young adults. Type 1 diabetes has an acute onset, with children and adolescents usually able to pinpoint when their diabetes symptoms began.
 
Since the pancreas can no longer produce insulin, people with type 1 diabetes require daily injections of insulin for life. Children with type 1 diabetes are at risk for long-term complications, including damage to the:
 
Type 1 diabetes accounts for 5 percent to 10 percent of all diagnosed cases of diabetes.
 
(Causes of Diabetes Continued: Page 2)
Written by/reviewed by: Arthur Schoenstadt, MD
Last reviewed by: Arthur Schoenstadt, MD