Cycloset Drug Interactions

It's important to note that drug interactions may occur if Cycloset is taken in combination with antipsychotics, sulfonamides, certain antidepressants, or a number of other medications. These interactions could make both medications less effective and may increase your risk for developing side effects.

 

An Overview of Cycloset Interactions

 Cycloset™ (bromocriptine mesylate) can potentially interact with several other medications. Some of these medicines that may lead to drug interactions with Cycloset include:
 

 

 

  • Chloramphenicol
     
  • CYP 3A4 inhibitor medications, including (but not limited to):

 

 

  • Ergot medications, such as:

 

    • Dihydroergotamine (Migranal®)
    • Ergotamine (Bellamine S, Cafergot®, Ergomar®)
    • Pergolide (Permax®)

 

 

    • Isosorbide dinitrate (BiDil®, Dilatrate® SR, Isochron™, Isordil®)
    • Isosorbide mononitrate (Imdur®, Ismo®, Monoket®)
    • Nitroglycerin tablets or capsules (Nitroquick®, Nitrostat®, Nitro-Time®)
    • Nitroglycerin ointment (Nitro-Bid®)
    • Nitroglycerin patches (Minitran®, Nitrodisc®, Nitro-Dur®, Transderm-Nitro®, Transderm-NTG®)
    • Nitroglycerin spray (Nitrolingual®)

 

  • Other dopamine agonists, such as:

 

 

  • Probenecid (Benuryl™)
     
  • Salicylates, such as aspirin (Ecotrin®, Bayer®, Anacin®), choline magnesium trisalicylate (Trilisate®), diflunisal (Dolobid®), and salsalate (Salflex®, Disalcid®, Amigesic®)
     
  • Sibutramine (Meridia®)
     
  • Sulfonamides ("sulfa drugs"), including sulfadiazine, sulfadoxine (Fansidar®), sulfamethoxazole (Bactrim®, Septra®), and sulfisoxazole (Gantrisin®)
     
  • Triptan migraine medications, such as:

 

 


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(Cycloset Drug Interactions Continued: Page 2)
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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