A healthcare provider may prescribe Avandia^® (rosiglitazone maleate) to help control blood sugar levels in people with type 2 diabetes. Avandia works by improving insulin sensitivity and lowering blood sugar. There are potential side effects of Avandia, including headaches, back pain, and swelling or water weight gain. Prior to taking Avandia, talk to your healthcare provider if you have heart problems of any kind, an upcoming surgery, or any allergies. Avandia tablets come in three different strengths: 2 mg, 4 mg, and 8 mg. The medication should be taken by mouth once or twice a day.