Avandaryl is a combination of two diabetes medicines (rosiglitazone and glimepiride) that are used to control blood sugar levels in people with type 2 diabetes. The medication works by helping your body to use its natural insulin better and by causing the pancreas to produce more insulin. Avandaryl comes in a tablet form that is usually taken once a day. As with any medication, there are potential side effects of Avandaryl, such as headaches, low blood sugar, and fluid retention.
(Click Avandaryl Uses for more information on what Avandaryl is used for, including possible off-label uses.)
Who Makes Avandaryl?
Avandaryl is manufactured by GlaxoSmithKline.
How Does Avandaryl Work?
Avandaryl is a combination of two diabetes medicines (rosiglitazone and glimepiride).
These two medications work differently and have different effects in the body:
Rosiglitazone is part of a group of medications called thiazolidinediones (or sometimes called "glitazones"). The drug helps to improve insulin sensitivity, meaning that it helps your body to use its natural insulin better. This helps to lower blood sugar and keep it under better control.
Glimepiride is part of a class of diabetes medications known as sulfonylureas. As a sulfonylurea, glimepiride helps the pancreas to produce more insulin. Glimepiride may also help the cells of the body respond to insulin better. Because of these effects, blood sugar levels decrease.
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