Avandaryl Drug Interactions

Avandaryl drug interactions with other medications, such as certain decongestants, some seizure medications, and oral contraceptives, can cause the body to metabolize the medications differently than intended and may lead to problems. Some of these drug interactions with Avandaryl can increase or decrease the level of Avandaryl in your blood or can make Avandaryl less effective. As a result, some of these interactions can increase your risk of side effects or increase your chance of high blood sugar. 

 

An Overview of Avandaryl Drug Interactions

 Avandaryl® (rosiglitazone and glimepiride) can potentially interact with several medicines. Some of the medicines that may lead to Avandaryl interactions include:
 
  • Atazanavir (Reyataz®)
     
  • Certain antifungals, including fluconazole (Diflucan®), ketoconazole (Nizoral®), and miconazole
     
  • Certain decongestants, such as phenylephrine (Sudafed PE®) or pseudoephedrine (Sudafed®)
     
  • Certain seizure medications, including:

o Carbamazepine (Tegretol®)

o Fosphenytoin (Cerebyx®)

o Phenobarbital (Luminal®)

o Phenytoin (Dilantin®)

o Primidone (Mysoline®)

  • Corticosteroids, such as:
o Betamethasone (Celestone®)
o Cortisone
o Dexamethasone (Decadron®)
o Fludrocortisone (Florinef®)
o Hydrocortisone (Cortef®)
o Methylprednisolone (Depo-Medrol®, Medrol®)
o Prednisolone (Ovapred®, Pediapred®)
o Triamcinolone (Kenalog®, Aristospan®)
  • Diuretics, such as:
o Acetazolamide (Diamox®)
o Chlorthalodone
o Promethazine (Phenergan®)
(Avandaryl Drug Interactions Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;