Avandaryl Drug Interactions
Avandaryl drug interactions with other medications, such as certain decongestants, some seizure medications, and oral contraceptives, can cause the body to metabolize the medications differently than intended and may lead to problems. Some of these drug interactions with Avandaryl can increase or decrease the level of Avandaryl in your blood or can make Avandaryl less effective. As a result, some of these interactions can increase your risk of side effects or increase your chance of high blood sugar.
In September 2010, the U.S. Food and Drug Administration (FDA) announced that it was severely restricting the use of Avandaryl, due to the risk of "cardiovascular events" such as heart attacks and strokes. Only individuals who could not control their diabetes on other medications (or those who were already taking the medication and doing well) would be able to take Avandaryl.
However, in November 2013, the FDA announced that a careful analysis of the research suggests that there is not, in fact, any increased risk, compared to treatment with standard diabetes medications and that the use of this medication will no longer be restricted.
An Overview of Avandaryl InteractionsAvandaryl® (rosiglitazone and glimepiride) can potentially interact with several medicines. Some of the medicines that may lead to Avandaryl interactions include:
- Atazanavir (Reyataz®)
- Certain antifungals, including fluconazole (Diflucan®), ketoconazole (Nizoral®), and miconazole
- Certain decongestants, such as phenylephrine (Sudafed PE®) or pseudoephedrine (Sudafed®)
- Certain seizure medications, including:
- Corticosteroids, such as:
- Diuretics, such as:
- Gemfibrozil (Lopid®)
- Niacin (nicotinic acid, Niaspan®, Niacor®, Nicolar®)
- Oral contraceptives (birth control pills)
- Phenothiazine medications, including: