Avandaryl Dosage

The Avandaryl dosage your healthcare provider prescribes will vary depending on several factors, such as how well your diabetes is controlled, other medical conditions you may have, and other medications you may be taking. Generally, the recommended starting Avandaryl dose is 4 mg/1 mg once daily with the first meal of the day. If necessary, your healthcare provider may slowly increase your Avandaryl dose up to a maximum dosage of Avandaryl 8 mg/4 mg once a day.

 

Avandaryl Dosing: An Introduction

Avandaryl® (rosiglitazone and glimepiride) is a combination of two different diabetes drugs: rosiglitazone maleate (Avandia®) and glimepiride (Amaryl®). The dose of Avandaryl your healthcare provider prescribes will vary depending on a number of factors, including:
 
  • How well your diabetes is controlled
  • Other medical conditions you may have
  • Other medications you may currently be taking.
     
As is always the case, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
 

Avandaryl Dosing for Type 2 Diabetes

The recommended starting Avandaryl dose is Avandaryl 4 mg/1 mg once daily with the first meal of the day.
 If you are switching from rosiglitazone (Avandia) or glimepiride (Amaryl), the starting dose can be as high as Avandaryl 4 mg/2 mg once daily. If you are already taking both Avandia and Amaryl, you should start at the equivalent combination dose of Avandaryl. The first part of the Avandaryl dosage refers to the rosiglitazone amount, while the second part of the dosage refers to the glimepiride amount (for example, Avandaryl 4 mg/1 mg contains 4 mg rosiglitazone and 1 mg glimepiride).
 
If necessary, your healthcare provider may slowly increase your Avandaryl dose to control blood sugar. The maximum dose is Avandaryl 8 mg/4 mg per day.
 
(Avandaryl Dosage Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;