Avandaryl and Blood Sugar
Avandaryl can cause low or high blood sugar levels in people taking the medication, and can even cause serious or life-threatening complications. Because prevention is the best treatment, people should be aware of the possible symptoms of high and low blood sugar levels while taking Avandaryl. Low blood sugar can cause symptoms such as sweating, extreme hunger, and dizziness. Symptoms of high blood sugar can include nausea, fatigue, and shortness of breath.
What Are the Effects of Avandaryl on Blood Sugar Levels?One of the possible side effects of Avandaryl® (rosiglitazone and glimepiride) is its effect on blood sugar levels. For some people, Avandaryl can cause blood sugar levels to drop too low (hypoglycemia). It is also possible for blood sugar to go too high (hyperglycemia) in people taking Avandaryl.
In September 2010, the U.S. Food and Drug Administration (FDA) announced that it was severely restricting the use of Avandaryl, due to the risk of "cardiovascular events" such as heart attacks and strokes. Only individuals who could not control their diabetes on other medications (or those who were already taking the medication and doing well) would be able to take Avandaryl.
However, in November 2013, the FDA announced that a careful analysis of the research suggests that there is not, in fact, any increased risk, compared to treatment with standard diabetes medications and that the use of this medication will no longer be restricted.