Avandamet Warnings and Precautions

There are many situations in which Avandamet should not be taken, as well as a number of Avandamet warnings and precautions you should be aware of before starting this drug. Since people with certain existing medical conditions should not take Avandamet, be sure to discuss your medical history with your healthcare provider prior to beginning treatment.

Avandamet Drug Info

In September 2010, the U.S. Food and Drug Administration (FDA) announced that it would be severely restricting the use of rosiglitazone, one of the active ingredients in Avandamet, due to the risk of "cardiovascular events" such as heart attacks and strokes. Only individuals who cannot control their diabetes on other medications (or those who are already taking the medication and doing well) will be able to take Avandamet.

Avandamet: What Should I Tell My Healthcare Provider?

Prior to taking Avandamet^® (

rosiglitazone and metformin), you should tell your healthcare provider if you have:

Heart problems of any kind, especially congestive heart failure (CHF)
Had a heart attack or stroke
Liver problems, including liver failure or cirrhosis
Low vitamin B₁₂ levels (pernicious anemia)
Kidney problems, including kidney failure (renal failure)
An upcoming surgery or procedure (including x-rays and other radiology procedures)
Any allergies, including allergies to food, dyes, or preservatives.

Also, let your healthcare provider know if you:

Are pregnant or thinking of becoming pregnant (see Avandamet and Pregnancy)
Are breastfeeding
Are having problems getting pregnant
Are premenopausal without regular menstrual periods
Drink alcohol.

Also, tell your healthcare provider about all other medicines you may be taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

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