Avandamet is a combination drug that is used for the treatment of type 2 diabetes. By improving insulin sensitivity and decreasing sugar absorption into the body, the prescription medicine has proven to be effective in reducing and controlling blood sugar levels. Because Avandamet has not been studied extensively in children, it has only been approved for use in adults. Occasionally, your healthcare provider may recommend off-label Avandamet uses, such as the treatment of polycystic ovarian syndrome.
In September 2010, the U.S. Food and Drug Administration (FDA) announced that it was severely restricting the use of Avandamet, due to the risk of "cardiovascular events" such as heart attacks and strokes. Only individuals who could not control their diabetes on other medications (or those who were already taking the medication and doing well) would be able to take Avandamet.
However, in November 2013, the FDA announced that a careful analysis of the research suggests that there is not, in fact, any increased risk, compared to treatment with standard diabetes medications and that the use of this medication will no longer be restricted.
Avandamet® (rosiglitazone and metformin) is a prescription medication that is used to treat type 2 diabetes. The drug is a combination of two different diabetes medications: rosiglitazone maleate (Avandia®) and metformin hydrochloride (Fortamet®, Glucophage®, Glucophage XR®, Glumetza®, or Riomet®).