Avandamet Side Effects (Cont.)

Avandamet Side Effects to Report

There are a number of less common (but more serious) side effects with Avandamet that you should report to your healthcare provider. These include, but are not limited to:
 
  • Signs of lactic acidosis (due to the metformin component of Avandamet), including feeling tired or weak, muscle pain, trouble breathing, stomach pain, feeling cold, dizziness or lightheadedness, and a slow or irregular heartbeat (see Metformin and Lactic Acidosis)
     
  • Symptoms of high blood sugar (see Avandamet and Blood Sugar), including:
o Increased hunger
o Increased thirst
o Increased urination
o Blurred vision
o Fatigue
o Shortness of breath
o Nausea or vomiting
  • Symptoms of low blood sugar, including
o Sweating
o Shakiness
o Extreme hunger
o Dizziness
o Cold sweats
o Blurry vision
o Changes in behavior, such as irritability
o Loss of coordination
o Difficulty speaking
o Confusion
  • Chest pain

 

 

  • Swelling, especially in the legs or ankles

 

  • Rapid increase in weight (three to five pounds in less than one week)

 

  • Liver problems, including
o Nausea or vomiting
o Stomach pain
o Unusual or unexplained tiredness
o Loss of appetite
o Dark urine
o Yellowing of your skin or the whites of your eyes
  • Vision changes

 

  • Signs of an allergic reaction, including unexplained skin rash, itching, hives, wheezing or trouble breathing, or unexplained swelling.
     
(Avandamet Side Effects Continued: Page 3)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;