Avandamet Drug Interactions

Avandamet drug interactions may potentially occur if the diabetes drug is taken with medicines such as: oral contraceptives, gemfibrozil, calcium channel blockers, or diuretics. Avandamet interactions may increase the drug levels in your blood, reduce the effectiveness of the medications, or increase the risk of side effects. These problems may require your healthcare provider to monitor you more closely or adjust your dosage as needed.

 

Avandamet Drug Interactions: An Overview

 Avandamet® (rosiglitazone and metformin) can potentially interact with several medicines. Some of the medicines that can lead to Avandamet drug interactions include:
 
  • Certain decongestants, such as phenylephrine (Sudafed PE®) or pseudoephedrine (Sudafed®)
     
  • Certain seizure medications, including
o Fosphenytoin (Cerebyx®)
o Phenobarbital (Luminal®)
o Betamethasone (Celestone®)
o Cortisone
o Dexamethasone (Decadron®)
o Fludrocortisone (Florinef®)
o Hydrocortisone (Cortef®)
o Methylprednisolone (Depo-Medrol®, Medrol®)
o Prednisolone (Ovapred®, Pediapred®)
o Triamcinolone (Kenalog®, Aristospan®)
  • Diuretics, such as:
o Acetazolamide (Diamox®)
o Chlorthalodone
o Promethazine (Phenergan®)
(Avandamet Drug Interactions Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;