Avandamet Dosage

For most people who are first beginning type 2 diabetes treatment with Avandamet, dosing usually starts at 2mg/500 mg once or twice a day. If you are switching from your existing rosiglitazone prescription or metformin prescription to the combination medicine, your new Avandamet dosage will depend on how much rosiglitazone or metformin you were previously taking. The maximum daily dose of Avandamet is 8 mg/2000 mg.

 

Avandamet Dosage: An Introduction

Avandamet® (rosiglitazone and metformin) is a combination of two different diabetes drugs: rosiglitazone maleate (Avandia®) and metformin hydrochloride (Fortamet®, Glucophage®, Glucophage XR®, Glumetza®, or Riomet®). The dose of Avandamet that your healthcare provider prescribes will vary depending on a number of factors, including:
 
  • How well your diabetes is controlled
  • Other medical conditions you may have
  • Other medications you may currently be taking.
     
As is always the case, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
 

Avandamet Dosing for People Not Taking Avandia or Metformin

For people who are not switching from rosiglitazone (Avandia®) or metformin (Glucophage®), the starting dose of Avandamet for type 2 diabetes treatment is Avandamet 2 mg/500 mg once or twice a day. Your healthcare provider may increase your dose slowly (up to a maximum of 8 mg/ 2000 mg total per day) if necessary.
 

Avandamet Dosage for People Switching From Metformin

For people switching to Avandamet from metformin (Fortamet, Glucophage, Glucophage XR, Glumetza, or Riomet), the Avandamet dose depends on the current metformin dose.
 For people taking 1000 mg of metformin total per day, the recommended starting dose is Avandamet 2 mg/500 mg twice daily. For people taking 2000 mg of metformin total per day, the recommended starting dose is Avandamet 2 mg/1000 mg twice daily. Your healthcare provider may increase your dose slowly up to 8 mg/2000 mg total per day if needed.
 
(Avandamet Dosage Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;