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When and How to Take Apidra

General considerations for when and how to take Apidra include the following:
  • This diabetes medication comes in an injectable form. It is injected just under the skin (subcutaneously) within 15 minutes before a meal or up to 20 minutes after starting it. Alternatively, Apidra can be used in an insulin pump.
  • Your healthcare provider should show you exactly how to inject Apidra. It can be injected into the skin and fat layer of the abdomen (stomach), upper arm, or thigh. Choose one of these three areas, and rotate injection sites within your chosen area, but do not rotate between different areas, as Apidra may be absorbed differently from various areas.
  • Apidra comes in vials, cartridges (for use in the Opticlik® pen device), or the prefilled SoloSTAR® pen. To use the pen devices, you will need specific types of needles known as "pen needles." Each time you inject Apidra, you will need to use a new needle. To use the drug from the vial, you will need insulin syringes with needles. 


  • If, for some reason, your Opticlik pen malfunctions, you can withdraw Apidra directly from the cartridge using an insulin syringe.
  • Because Apidra is a solution, not a suspension, you don't need to shake or swirl it.
  • Studies have shown that Apidra can be mixed with NPH insulin. You should not mix Apidra with any other type of insulin other than NPH. If you use Apidra in an insulin pump, never mix it with another insulin or dilute it.
  • For this diabetes drug to work properly, it must be taken as prescribed. Apidra will not work if you stop taking it. Make sure to monitor your blood sugar levels as your healthcare provider recommends.
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