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Amaryl and Pregnancy

Amaryl may not be safe for women who are pregnant. The FDA has classified Amaryl as a pregnancy Category C medicine, meaning that it does appear to cause harm to the fetus in animal studies. Be sure to talk to your doctor about Amaryl and pregnancy; keep in mind that your doctor may still prescribe Amaryl if the benefits to you outweigh any possible risks to the unborn child.

An Overview of Amaryl and Pregnancy

For people who are pregnant, Amaryl® (glimepiride) may not be safe. This is based on animal studies that looked at the effects of Amaryl during pregnancy.

Amaryl and Pregnancy Category C

The U.S. Food and Drug Administration (FDA) uses a pregnancy category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category C is given to medicines that have not been studied in pregnant humans, but do appear to cause harm to the fetus in animal studies. Also, medicines that have not been studied in any pregnant women or animals are automatically given a pregnancy Category C rating.
When given to pregnant rats and rabbits, Amaryl caused an increase in miscarriages. Amaryl did not cause any birth defects. It is important to note that animals do not always respond to medicines in the same way that humans do. Therefore, a pregnancy Category C medicine may be given to a pregnant woman if the healthcare provider believes that the benefits to the woman outweigh any possible risks to the unborn child.

Recommendations for Amaryl and Pregnancy

If you are pregnant or thinking about becoming pregnant, let your healthcare provider know. Your healthcare provider will consider both the benefits and the risks of taking Amaryl during pregnancy before making a recommendation for your particular situation.
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