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Actos Drug Interactions

Atorvastatin (Lipitor)
In studies, taking Actos with atorvastatin decreased the level of both Actos and atorvastatin in the blood, perhaps making them both less effective. Your healthcare provider may need to adjust your dose of these medications.
 
Certain Seizure Medications
Taking Actos with certain seizure medications can decrease the level of Actos in your blood, perhaps making it less effective. Your healthcare provider may need to increase your dose of Actos.
 
Gemfibrozil (Lopid)
Taking Actos with gemfibrozil can increase the level of Actos in your blood, increasing your risk of side effects. Your healthcare provider may need to decrease your dose of Actos.
 
Ketoconazole (Nizoral)
In studies, taking Actos with ketoconazole increased the level of Actos in the blood, which could increase the risk of side effects. Your healthcare provider may need to adjust your dose of these medications.
 
Midazolam (Versed)
Taking Actos and midazolam together can decrease the level of midazolam in your blood, perhaps making it less effective. Your healthcare provider may need to increase the dose of midazolam in order to achieve the desired effects.
 
Nifedipine (Adalat, Procardia)
In studies, taking Actos with nifedipine decreased the level of nifedipine in the blood, perhaps making it less effective. Your healthcare provider may need to adjust your dose of these medications.
 
Oral Contraceptives
In studies, taking Actos with oral contraceptives (birth control pills) decreasd the level of oral contraceptive in the blood. It is not clear if this decrease would reduce the effectiveness of oral contraceptives. Your healthcare provider may need to adjust your dose of these medications or suggest different birth control options.
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Actos Drug Info

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