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How Does Actoplus Met Work?

People who have type 2 diabetes -- also called adult-onset diabetes or noninsulin-dependent diabetes -- may choose to use Actoplus Met® (pioglitazone and metformin). It works in several different ways. The pioglitazone component helps improve insulin sensitivity, and the metformin component helps the body respond to its own insulin better and causes a decrease in blood sugar levels.
Because of how Actoplus Met works, people taking it often see an improvement in HbA1c and fasting blood sugar test results. These are two important measurements that healthcare providers use to determine how well a particular diabetes drug is working. Actoplus Met caused a 0.64 percent decrease in HbA1c levels and a decrease of 42.8 mg/dL in fasting blood sugar levels in clinical studies, compared to people taking just the metformin component alone.
(Click Actoplus Met to learn more about this drug, including exactly how it works, what you need to know before beginning treatment, what to do in cases of overdose, and possible side effects.)
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