Actoplus Met Warnings and Precautions

It's important to be aware of Actoplus Met warnings and precautions before taking it, including information on who should not take Actoplus Met and side effects that may occur. Side effects can include lactic acidosis, fluid retention, decreased vitamin B12 levels, and increased liver enzymes. Actoplus Met warnings and precautions also extend to those who have kidney disease, have metabolic or diabetic ketoacidosis, or are seriously dehydrated.

 

Actoplus Met: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking
 Actoplus Met® (pioglitazone and metformin) if you have:
 
  • Heart problems of any kind, especially congestive heart failure (CHF)
  • Had a heart attack or stroke
  • Liver problems, including liver failure or cirrhosis
  • Low vitamin B12 levels (pernicious anemia)
  • Kidney problems, including kidney failure (renal failure)
  • An upcoming surgery or procedure (including x-rays and other radiology procedures)
  • Any allergies, including allergies to food, dyes, or preservatives.
     
Also let your healthcare provider know if you:
 
  • Are pregnant or thinking of becoming pregnant (see Actoplus Met and Pregnancy)
  • Are breastfeeding
  • Are having problems getting pregnant
  • Are premenopausal without regular menstrual periods
  • Drink alcohol.
     
In addition, tell your healthcare provider about all other medicines you may be taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 
(Actoplus Met Warnings and Precautions Continued: Page 2)
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;