Actoplus Met Side Effects
Swelling, upper respiratory tract infections, and weight gain are some of the more common Actoplus Met side effects. These are generally considered minor and do not require medical attention. However, you should contact your healthcare provider immediately if you develop serious side effects of Actoplus Met, such as chest pain, signs of low blood sugar, vision changes, or an allergic reaction.
As with any medicine, side effects are possible with Actoplus Met® (pioglitazone and metformin). However, not everyone who takes the drug will experience side effects. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or can be easily treated by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Actoplus Met. Your healthcare provider can discuss a more complete list of Actoplus Met side effects with you.)
Actoplus Met has been studied thoroughly in clinical trials in which side effects of a group of people taking the drug are documented and compared to another group not taking the medicine. This way, it is possible to see what side effects occur, how often they appear, and how they compare to the group not taking the medicine.
Based on these studies, the most common Actoplus Met side effects include:
- Upper respiratory tract infections (similar to the common cold or flu) -- in up to 13.5 percent of people
- Swelling or fluid retention (edema) of the lower leg or ankles -- up to 11.3 percent
- Weight gain -- up to 6.7 percent (see Actoplus Met and Weight Gain)
- Diarrhea -- up to 5.8 percent
- Nausea -- up to 5.8 percent
- Urinary tract infections (UTI), including bladder infections -- up to 5.8 percent
- Dizziness -- up to 5.4 percent
- Headache -- up to 5.3 percent
- Sinus infection or irritation -- up to 5 percent.